|Other Names||Receptor-interacting serine/threonine-protein kinase 4, Ankyrin repeat domain-containing protein 3, PKC-delta-interacting protein kinase, RIPK4, ANKRD3, DIK|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7808b was selected from the C-term region of human ANKRD3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
Hattori, M., et al., Nature 405(6784):311-319 (2000).
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