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ZPK Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q12852
Clone Names 3021009
Peptide ID 3021009
Additional Information
Gene ID 7786
Other Names Mitogen-activated protein kinase kinase kinase 12, Dual leucine zipper bearing kinase, DLK, Leucine-zipper protein kinase, ZPK, MAPK-upstream kinase, MUK, Mixed lineage kinase, MAP3K12, ZPK
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7811a was selected from the Center region of human ZPK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP3K12
Synonyms ZPK
Function May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein
Tissue Location Highly expressed in brain and kidney.
Research Areas
Citations (0)

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ZPK, a member of the Ser/Thr protein kinase family (MAP kinase kinase kinase subfamily), may be an activator of the JNK/SAPK pathway. It phosphorylates beta-casein, histone 1 and myelin basic protein in vitro, and interacts with MBIP through the leucine-zipper motif. ZPK is highly expressed in brain and kidney. It is phosphorylated in cytosol under basal conditions and dephosphorylated when membrane-associated.


Fukuyama, K., et al., J. Biol. Chem. 275(28):21247-21254 (2000).Reddy, U.R., et al., Biochem. Biophys. Res. Commun. 202(1):613-620 (1994).

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$ 80.00
Cat# BP7811a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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