VARS Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P26640 |
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Clone Names | 71228148 |
Gene ID | 7407 |
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Other Names | Valine--tRNA ligase, Protein G7a, Valyl-tRNA synthetase, ValRS, VARS, G7A, VARS2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7843c was selected from the Center region of human VARS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | VARS1 (HGNC:12651) |
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Synonyms | G7A, VARS, VARS2 |
Function | Catalyzes the attachment of valine to tRNA(Val). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. This protein belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.
References
Jiang,S., FEBS Lett. 579 (27), 6049-6054 (2005)Bonnefond,L., Biochemistry 44 (12), 4805-4816 (2005)Xie,T., Genome Res. 13 (12), 2621-2636 (2003)
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