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ESRRG Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P62508
Clone Names 80311222
Additional Information
Gene ID 2104
Other Names Estrogen-related receptor gamma, ERR gamma-2, Estrogen receptor-related protein 3, Nuclear receptor subfamily 3 group B member 3, ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7870c was selected from the Center region of human ESRRG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ESRRG
Synonyms ERR3, ERRG2, KIAA0832, NR3B3
Function Orphan receptor that acts as a transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity). Induces the expression of PERM1 in the skeletal muscle.
Cellular Location Nucleus.
Tissue Location Expressed in the heart, kidney, brain, lung, bone marrow, adrenal gland, trachea, spinal cord and thyroid gland
Research Areas
Citations (0)
citation

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Background

ESRRG is an orphan receptor that acts as transcription activator in the absence of bound ligand. This protein binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements.

References

Chen F., Zhang Q., McDonald T.Gene 228:101-109(1999)Heard D.J., Norby P.L.Mol. Endocrinol. 14:382-392(2000)Hong H., Yang L., Stallcup M.R.J. Biol. Chem. 274:22618-22626(1999)

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$ 277.78
Cat# BP7870c
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Availability: 2 weeks
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