|Other Names||Bcl-2-like protein 13, Bcl2-L-13, Bcl-rambo, Protein Mil1, BCL2L13, MIL1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7878c was selected from the Center region of human BCL2L13. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May promote the activation of caspase-3 and apoptosis.|
|Cellular Location||Isoform 2: Mitochondrion membrane; Single-pass membrane protein. Nucleus|
|Tissue Location||Ubiquitous, with the highest levels of expression in heart, placenta and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein may promote the activation of caspase-3 and apoptosis.
Banga,S., Proc. Natl. Acad. Sci. U.S.A. 104 (12), 5121-5126 (2007)Yi,P., FEBS Lett. 534 (1-3), 61-68 (2003)Kataoka,T., J. Biol. Chem. 276 (22), 19548-19554 (2001)
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