|Other Names||Cytochrome P450 2U1, CYP2U1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7889c was selected from the Center region of human CYP2U1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane|
|Tissue Location||Widely expressed with stronger expression in thymus, heart and cerebellum.|
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Provided below are standard protocols that you may find useful for product applications.
CYP2U1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids.
Karlgren,M., Biochem. Biophys. Res. Commun. 315 (3), 679-685 (2004)Chuang,S.S., J. Biol. Chem. 279 (8), 6305-6314 (2004)
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