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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MAP2K5 Antibody (S149) Blocking peptide   

MAP2K5 Antibody (S149) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q13163
Clone Names 109102
Peptide ID 109102
Additional Information
Gene ID 5607
Other Names Dual specificity mitogen-activated protein kinase kinase 5, MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5, MEK 5, MAP2K5, MEK5, MKK5, PRKMK5
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7906f was selected from the S149 region of human MAP2K5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP2K5
Synonyms MEK5, MKK5, PRKMK5
Function Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.
Tissue Location Expressed in many adult tissues. Abundant in heart and skeletal muscle
Research Areas
Citations (0)

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MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.


Raviv,Z.,J. Cell. Sci. 117 (PT 9), 1773-1784 (2004)Kato,Y.,EMBO J. 16 (23), 7054-7066 (1997)English,J.M.,J. Biol. Chem. 274 (44), 31588-31592 (1999)

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$ 80.00
Cat# BP7906f
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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