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PKN beta Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6P5Z2
Other Accession NP_037487
Clone Names 2032205
Peptide ID 2032205
Additional Information
Gene ID 29941
Other Names Serine/threonine-protein kinase N3, Protein kinase PKN-beta, Protein-kinase C-related kinase 3, PKN3, PKNBETA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7935a was selected from the C-term region of human PKN beta . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PKN3
Synonyms PKNBETA
Function Contributes to invasiveness in malignant prostate cancer.
Cellular Location Nucleus. Cytoplasm, perinuclear region Note=Nuclear and perinuclear Golgi region
Tissue Location Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues
Research Areas
Citations (0)

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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).


Oishi, K., et al., Biochem. Biophys. Res. Commun. 261(3):808-814 (1999).

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$ 80.00
Cat# BP7935a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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