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RSK3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q15349
Clone Names 2032505
Additional Information
Gene ID 6196
Other Names Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, RPS6KA2, MAPKAPK1C, RSK3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7943a was selected from the C-term region of human RSK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS6KA2
Synonyms MAPKAPK1C, RSK3
Function Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
Cellular Location Nucleus. Cytoplasm
Tissue Location Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate
Research Areas
Citations (0)

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RSK3, a member of the S6 kinase subfamily of Ser/Thr protein kinases, phosphorylates a wide range of substrates including ribosomal protein S6. It is implicated in the activation of the mitogen-activated kinase cascade. This nuclear protein is expressed in many tissues, with highest expression in lung and skeletal muscle.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Zhao, Y., et al., Mol. Cell. Biol. 15(8):4353-4363 (1995).Moller, D.E., et al., Am. J. Physiol. 266 (2 Pt 1), C351-C359 (1994).

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$ 80.00
Cat# BP7943a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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