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GARS Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P41250
Other Accession NP_002038
Clone Names 7010868
Peptide ID 7010868
Additional Information
Gene ID 2617
Other Names Glycine--tRNA ligase, Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS, GARS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7952b was selected from the C-term region of human GARS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.
Cellular Location Cytoplasm. Mitochondrion. Cell projection, axon Note=Associated with granules in cultured neuron cells
Tissue Location Widely expressed, including brain and spinal cord.
Research Areas
Citations (0)

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GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.


Shiba K., Schimmel P.J. Biol. Chem. 269:30049-30055(1994) Antonellis A., Ellsworth R.E.Am. J. Hum. Genet. 72:1293-1299(2003)

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$ 80.00
Cat# BP7952b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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