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YSK Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00506
Clone Names 2032701
Peptide ID 2032701
Additional Information
Gene ID 10494
Other Names Serine/threonine-protein kinase 25, Ste20-like kinase, Sterile 20/oxidant stress-response kinase 1, SOK-1, Ste20/oxidant stress response kinase 1, STK25, SOK1, YSK1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7956a was selected from the C-term region of human YSK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name STK25
Synonyms SOK1, YSK1
Function Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.
Cellular Location Cytoplasm. Golgi apparatus. Note=Localizes to the Golgi apparatus
Tissue Location Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung
Research Areas
Citations (0)

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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.


Osada, S., et al., Oncogene 14(17):2047-2057 (1997).Pombo, C.M., et al., EMBO J. 15(17):4537-4546 (1996).

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$ 80.00
Cat# BP7956a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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