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GAK Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6P490
Clone Names 3051210
Peptide ID 3051210
Additional Information
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8061a was selected from the N-term region of human GAK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Q6P490
Research Areas
Citations (0)

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GAK, a member of the Ser/Thr protein kinase family, associates with cyclin G and CDK5. It appears to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. GAK localizes to the perinuclear area and to the trans-Golgi network. It is also observed on the plasma membrane, probably at focals adhesions. Expression is ubiquitous, wiht highest levels in testis. The protein contains 1 J domain and 1 tensin domain.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Greener, T., et al., J. Biol. Chem. 275(2):1365-1370 (2000).Kimura, S.H., et al., Genomics 44(2):179-187 (1997).

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$ 80.00
Cat# BP8061a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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