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KIST (KIS) Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TAS1
Clone Names 4012611
Additional Information
Gene ID 127933
Other Names Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1, UHMK1, KIS, KIST
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8067b was selected from the N-term region of human KIS . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name UHMK1
Synonyms KIS, KIST
Function Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes
Research Areas
Citations (0)
citation

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Background

Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.

References

Bieche, I., et al., Brain Res. Mol. Brain Res. 114(1):55-64 (2003).Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Boehm, M., et al., EMBO J. 21(13):3390-3401 (2002).

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$ 277.78
Cat# BP8067b
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Availability: 2 weeks
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