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NME6 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75414 |
|---|---|
| Clone Names | 3033103 |
| Gene ID | 10201 |
|---|---|
| Other Names | Nucleoside diphosphate kinase 6, NDK 6, NDP kinase 6, Inhibitor of p53-induced apoptosis-alpha, IPIA-alpha, nm23-H6, NME6 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8083a was selected from the N-term region of human NME6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NME6 |
|---|---|
| Function | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. |
| Tissue Location | Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen |
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Provided below are standard protocols that you may find useful for product applications.
Background
NME6 plays a major role in the synthesis of nucleoside triphosphates other than ATP. It is an inhibitor of p53-induced apoptosis. NME6 is expressed at a moderately low level in many tissues, most abundantly in kidney, prostate, ovary, intestine, and spleen.
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Mehus, J.G., et al., Hum. Genet. 104(6):454-459 (1999).
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