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Natriuretic Peptide Receptor C Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P17342
Clone Names 3031011
Peptide ID 3031011
Additional Information
Gene ID 4883
Other Names Atrial natriuretic peptide receptor 3, Atrial natriuretic peptide clearance receptor, Atrial natriuretic peptide receptor type C, ANP-C, ANPR-C, NPR-C, NPR3, ANPRC, C5orf23, NPRC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8113a was selected from the N-term region of human ANPC . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPR3
Synonyms ANPRC, C5orf23, NPRC
Function Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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ANPC is a receptor for atrial natriuretic peptide. It does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.


Porter, J.G., et al., Biochem. Biophys. Res. Commun. 171(2):796-803 (1990).Lowe, D.G., et al., Nucleic Acids Res. 18 (11), 3412 (1990).

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$ 80.00
Cat# BP8113a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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