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AK3 Antibody (C-term T208) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P27144
Clone Names 4011610
Peptide ID 4011610
Additional Information
Gene ID 205
Other Names Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170}, AK 4 {ECO:0000255|HAMAP-Rule:MF_03170}, 27410 {ECO:0000255|HAMAP-Rule:MF_03170}, 2746 {ECO:0000255|HAMAP-Rule:MF_03170}, Adenylate kinase 3-like {ECO:0000255|HAMAP-Rule:MF_03170}, GTP:AMP phosphotransferase AK4 {ECO:0000255|HAMAP-Rule:MF_03170}, AK4 {ECO:0000255|HAMAP-Rule:MF_03170}
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8132d was selected from the C-term region of human AK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AK4 {ECO:0000255|HAMAP-Rule:MF_03170}
Function Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
Cellular Location Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03170, ECO:0000269|PubMed:11485571, ECO:0000269|PubMed:19766732}
Tissue Location Highly expressed in kidney, moderately expressed in heart and liver and weakly expressed in brain
Research Areas
Citations (0)

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AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for the AK3 gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene, which sequence alignment suggests is located on chromosome 1.


Biochem. J. 358 (PT 1), 225-232 (2001)Eur. J. Biochem. 261(2):509-517 (1999). Brain Res. Mol. Brain Res. 62(2):187-195 (1998). Genomics 13(3):537-542 (1992). Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982).

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$ 80.00
Cat# BP8132d
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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