|Other Names||Hexokinase-3, Hexokinase type III, HK III, HK3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8139d was selected from the N-term region of human HK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate.
Sui, D., et al., Arch. Biochem. Biophys. 382(2):262-274 (2000). Lowes, W., et al., Biochim. Biophys. Acta 1379(1):134-142 (1998). Furuta, H., et al., Genomics 36(1):206-209 (1996). Palma, F., et al., Mol. Cell. Biochem. 155(1):23-29 (1996). Colosimo, A., et al., Cytogenet. Cell Genet. 74(3):187-188 (1996).
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