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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   YWHAZ Antibody (D231) Blocking peptide   

YWHAZ Antibody (D231) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P63104
Other Accession P29312
Clone Names 3053009
Peptide ID 3053009
Additional Information
Gene ID 7534
Other Names 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8152b was selected from the C-term region of human 14-3-3 protein zeta/delta . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Cellular Location Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes
Research Areas
Citations (0)

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YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.


Powell, D.W., et al., Mol. Cell. Biol. 23(15):5376-5387 (2003).Zhu, P., et al., Biochem. Biophys. Res. Commun. 301(4):991-999 (2003).Li, Y., et al., J. Biol. Chem. 277(47):44593-44596 (2002).Wang, H., et al., J. Clin. Endocrinol. Metab. 87(6):2629-2634 (2002).Nellist, M., et al., J. Biol. Chem. 277(42):39417-39424 (2002).

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$ 80.00
Cat# BP8152b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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