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AK1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P00568
Clone Names 3060403
Peptide ID 3060403
Additional Information
Gene ID 203
Other Names Adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}, AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}, 2743 {ECO:0000255|HAMAP-Rule:MF_03171}, 2746 {ECO:0000255|HAMAP-Rule:MF_03171}, ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}, Myokinase {ECO:0000255|HAMAP-Rule:MF_03171}, AK1 {ECO:0000255|HAMAP-Rule:MF_03171}
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8160b was selected from the C-term region of human AK1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AK1 {ECO:0000255|HAMAP-Rule:MF_03171}
Function Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.


Corrons, J.L., et al., Blood 102(1):353-356 (2003).Toren, A., et al., Br. J. Haematol. 87(2):376-380 (1994).Zuffardi, O., et al., Hum. Genet. 82(1):17-19 (1989).Matsuura, S., et al., J. Biol. Chem. 264(17):10148-10155 (1989).Miwa, S., et al., Am. J. Hematol. 14(4):325-333 (1983).

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$ 80.00
Cat# BP8160b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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