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Kif5B-1 Antibody (Central) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P33176
Other Accession NP_004512
Clone Names 4111103
Additional Information
Gene ID 3799
Other Names Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIF5B, KNS, KNS1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8170c was selected from the Central region of human Kif5B-1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIF5B
Synonyms KNS, KNS1
Function Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
Cellular Location Cytoplasm, cytoskeleton. Note=Uniformly distributed between soma and neurites in hippocampal neurons.
Research Areas
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Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. It is composed of an oligomer consisting of two heavy chains and two light chains. Kinesin, which is thought to interact with GRIP1, possesses three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles. Kinesin is found in newborn and adult brain, liver, kidney, spleen, heart, lung and sciatic nerve.


Diefenbach, R.J., et al., Biochem. Biophys. Res. Commun. 319(3):987-992 (2004).Diefenbach, R.J., et al., Biochemistry 41(50):14906-14915 (2002).Hakimi, M.A., et al., J. Biol. Chem. 277(40):36909-36912 (2002).Tanaka, Y., et al., Cell 93(7):1147-1158 (1998).Rahman, A., et al., J. Biol. Chem. 273(25):15395-15403 (1998).

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$ 80.00
Cat# BP8170c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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