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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (Center) Blocking peptide   

Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q02153
Other Accession NP_000848
Clone Names 5030109
Additional Information
Gene ID 2983
Other Names Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8171c was selected from the Center region of human GUCY1B3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUCY1B3
Synonyms GUC1B3, GUCSB3, GUCY1B1
Function Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P16068}.
Tissue Location Detected in brain cortex and cerebellum (at protein level).
Research Areas
Citations (0)

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Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.


Russwurm, M., et al., J. Biol. Chem. 276(48):44647-44652 (2001).Lucas, K.A., et al., Pharmacol. Rev. 52(3):375-414 (2000).Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).Giuili, G., et al., FEBS Lett. 304(1):83-88 (1992).

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$ 80.00
Cat# BP8171c
Availability: In Stock
Bulk Size
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