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BAI3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O60242
Other Accession NP_001695
Additional Information
Gene ID 577
Other Names Brain-specific angiogenesis inhibitor 3, BAI3, KIAA0550
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8172a was selected from the C-term region of human BAI3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BAI3
Synonyms KIAA0550
Function May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines
Research Areas
Citations (0)

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Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.


Shiratsuchi, T., et al., Cytogenet. Cell Genet. 79 (1-2), 103-108 (1997).

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$ 80.00
Cat# BP8172a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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