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MEG1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P29074
Clone Names 1121001
Peptide ID 1121001
Additional Information
Gene ID 5775
Other Names Tyrosine-protein phosphatase non-receptor type 4, Protein-tyrosine phosphatase MEG1, MEG, PTPase-MEG1, PTPN4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8407a was selected from the Center region of human MEG1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN4
Function May act at junctions between the membrane and the cytoskeleton.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton
Research Areas
Citations (0)

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MEG1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.


Hironaka, K., et al., J. Biol. Chem. 275(21):16167-16173 (2000).Gu, M., et al., Proc. Natl. Acad. Sci. U.S.A. 93(23):12980-12985 (1996).Gu, M., et al., J. Biol. Chem. 271(44):27751-27759 (1996).Gu, M.X., et al., Proc. Natl. Acad. Sci. U.S.A. 88(13):5867-5871 (1991).

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$ 80.00
Cat# BP8407a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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