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PTPIA2 beta Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q92932
Clone Names 2011602
Peptide ID 2011602
Additional Information
Gene ID 5799
Other Names Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin, PTPRN2, KIAA0387
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8427a was selected from the N-term region of human PTPIA2beta . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0387
Function Implicated in development of nervous system and pancreatic endocrine cells.
Cellular Location Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type I membrane protein
Tissue Location Highest levels in brain and pancreas. Lower levels in trachea, prostate, stomach and spinal chord
Research Areas
Citations (0)

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PTPIA2beta is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus.


Schmidli, R.S., et al., Autoimmunity 28(1):15-23 (1998).Li, Q., et al., Proc. Assoc. Am. Physicians 109(4):429-439 (1997).Cui, L., et al., J. Biol. Chem. 271(40):24817-24823 (1996).Kawasaki, E., et al., Biochem. Biophys. Res. Commun. 227(2):440-447 (1996).Smith, P.D., et al., Biochem. Biophys. Res. Commun. 229(2):402-411 (1996).

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$ 80.00
Cat# BP8427a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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