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DUSP7 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16829
Other Accession NP_001938
Peptide ID 15304
Additional Information
Gene ID 1849
Other Names Dual specificity protein phosphatase 7, Dual specificity protein phosphatase PYST2, DUSP7, PYST2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8450a was selected from the N-term region of human DUSP7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP7
Synonyms PYST2
Function Regulates the activity of the MAP kinase family in response to changes in the cellular environment. PYST2-S may act as a negative regulator of PYST2-L although it is unclear whether this is by competing for transcription, translation or activation factors.
Cellular Location Cytoplasm.
Tissue Location Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells.
Research Areas
Citations (0)

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DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.


Immunol. Lett. 92 (1-2), 149-156 (2004)Oncogene 22 (48), 7649-7660 (2003)Meth. Enzymol. 366, 103-113 (2003)J. Cell. Sci. 111 (PT 22), 3389-3399 (1998)EMBO J. 15 (14), 3621-3632 (1996)

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$ 80.00
Cat# BP8450a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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