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DUSP13-L184 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UII6
Clone Names 4021106
Peptide ID 4021106
Additional Information
Gene ID 51207
Other Names Dual specificity protein phosphatase 13 isoform B, DUSP13B, Dual specificity phosphatase SKRP4, Testis- and skeletal-muscle-specific DSP, DUSP13, DUSP13B, TMDP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8455b was selected from the C-term region of human DUSP13-L184. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP13
Synonyms DUSP13B, TMDP
Function Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro.
Tissue Location Most abundantly expressed in the testis. Also found in the skeletal muscle. Testis-specific (at protein level)
Research Areas
Citations (0)

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Dual-specificity phosphatases, a subfamily of protein-tyrosine phosphatases, play important roles in signal transduction, cell cycle progression, and tumor suppression. The cDNA encoding a novel phosphatase,PIR1,phosphatase that interacts with RNA/RNP complex 1. Sequence analysis revealed that the predicted 329-amino acid protein has homology to several dual-specificity phosphatases and contains 2 stretches of arginine-rich sequence similar to those found in some RNA-binding proteins. In vitro, recombinant protein displays protein-tyrosine phosphatase activity and binds directly to RNA.


Nakamura K., Shima H., Watanabe M., Haneji T., Kikuchi K.Biochem. J. 344:819-825(1999).Deloukas et al. Nature 429:375-381(2004).Strausberg et al. Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).

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$ 80.00
Cat# BP8455b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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