|Other Names||Dual specificity protein phosphatase 21, Low molecular weight dual specificity phosphatase 21, LMW-DSP21, DUSP21, LMWDSP21|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8481c was selected from the Center region of human DUSP21. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.|
|Cellular Location||Cytoplasm. Nucleus. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side|
|Tissue Location||Expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
DUSP21 is member of the dual-specificity phosphatase (DSP) family, which catalyzes dephosphorylation of phosphotyrosine and phosphothreonine residues.
Hood,K.L., Biochem. Biophys. Res. Commun. 298 (4), 545-551 (2002)
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