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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PTPN7 (PTN7) Antibody (Center) Blocking peptide   

PTPN7 (PTN7) Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P35236
Clone Names 4092954
Peptide ID 4092954
Additional Information
Gene ID 5778
Other Names Tyrosine-protein phosphatase non-receptor type 7, Hematopoietic protein-tyrosine phosphatase, HEPTP, Protein-tyrosine phosphatase LC-PTP, PTPN7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8483c was selected from the Center region of human PTN7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN7
Function Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton
Tissue Location Expressed exclusively in thymus and spleen.
Research Areas
Citations (0)

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PTN7 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processesincluding cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway.

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$ 80.00
Cat# BP8483c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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