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LTA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P01374
Clone Names 90504097
Peptide ID 90504097
Additional Information
Gene ID 4049
Other Names Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8509c was selected from the Center region of human LTA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTA
Synonyms TNFB, TNFSF1
Function Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Cellular Location Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated
Research Areas
Citations (0)

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LTA, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.


Buonaguro,L.,, J. Virol. 66 (12), 7159-7167 (1992)Fukushima,K.,, Arch. Biochem. Biophys. 304 (1), 144-153 (1993)

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$ 80.00
Cat# BP8509c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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