ARHGEF10 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O15013 |
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Clone Names | 90429025 |
Gene ID | 9639 |
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Other Names | Rho guanine nucleotide exchange factor 10, ARHGEF10, KIAA0294 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8513c was selected from the Center region of human ARHGEF10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ARHGEF10 |
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Synonyms | KIAA0294 |
Function | May play a role in developmental myelination of peripheral nerves. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. This protein may form complex with G proteins and stimulate Rho-dependent signals.
References
Mohl,M., et.al., Naunyn Schmiedebergs Arch. Pharmacol. 373 (5), 333-341 (2006)Verhoeven,K., et.al., Am. J. Hum. Genet. 73 (4), 926-932 (2003)
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