Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
AKAP3 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O75969 |
|---|---|
| Clone Names | 90819088 |
| Gene ID | 10566 |
|---|---|
| Other Names | A-kinase anchor protein 3, AKAP-3, A-kinase anchor protein 110 kDa, AKAP 110, Cancer/testis antigen 82, CT82, Fibrous sheath protein of 95 kDa, FSP95, Fibrousheathin I, Fibrousheathin-1, Protein kinase A-anchoring protein 3, PRKA3, Sperm oocyte-binding protein, AKAP3, AKAP110, SOB1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8515c was selected from the Center region of human AKAP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AKAP3 |
|---|---|
| Synonyms | AKAP110, SOB1 |
| Function | Has a role in the maintenance of acrosome structure (PubMed:35228300). May function as a regulator of both spermatozoa motility and head-associated functions such as capacitation and the acrosome reaction. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment |
| Tissue Location | Testis specific; only expressed in spermatids. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
AKAP3 may function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction.
References
Lefevre,A.,et.al., Biochem. Biophys. Res. Commun. 259 (1), 60-66 (1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Shipping Information
