|Other Names||A-kinase anchor protein 3, AKAP-3, A-kinase anchor protein 110 kDa, AKAP 110, Cancer/testis antigen 82, CT82, Fibrous sheath protein of 95 kDa, FSP95, Fibrousheathin I, Fibrousheathin-1, Protein kinase A-anchoring protein 3, PRKA3, Sperm oocyte-binding protein, AKAP3, AKAP110, SOB1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8515c was selected from the Center region of human AKAP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment|
|Tissue Location||Testis specific; only expressed in spermatids.|
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Provided below are standard protocols that you may find useful for product applications.
AKAP3 may function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction.
Lefevre,A.,et.al., Biochem. Biophys. Res. Commun. 259 (1), 60-66 (1999)
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