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THBS1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07996
Clone Names 90415134
Peptide ID 90415134
Additional Information
Gene ID 7057
Other Names Thrombospondin-1, THBS1, TSP, TSP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8522a was selected from the N-term region of human THBS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name THBS1
Synonyms TSP, TSP1
Function Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
Cellular Location Endoplasmic reticulum. Sarcoplasmic reticulum
Research Areas
Citations (0)

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THBS1 is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.


Hofsteenge,J.,, J. Biol. Chem. 276 (9), 6485-6498 (2001)Roszmusz,E.,, Biochem. Biophys. Res. Commun. 296 (1), 156-160 (2002)

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$ 80.00
Cat# BP8522a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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