LRPAP1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P30533 |
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Clone Names | 90625113 |
Gene ID | 4043 |
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Other Names | Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP, LRPAP1, A2MRAP |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8529b was selected from the C-term region of human LRPAP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LRPAP1 (HGNC:6701) |
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Synonyms | A2MRAP |
Function | Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. |
Cellular Location | Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis- Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. Note=May be associated with receptors at the cell surface. |
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Provided below are standard protocols that you may find useful for product applications.
Background
LRPAP1 interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
References
Lisi,S., et.al., J. Endocrinol. Invest. 30 (10), 839-843 (2007)Vertegaal,A.C., et.al., Mol. Cell Proteomics 5 (12), 2298-2310 (2006)
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