|Other Names||Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP, LRPAP1, A2MRAP|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8529b was selected from the C-term region of human LRPAP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.|
|Cellular Location||Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. Note=May be associated with receptors at the cell surface.|
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Provided below are standard protocols that you may find useful for product applications.
LRPAP1 interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
Lisi,S., et.al., J. Endocrinol. Invest. 30 (10), 839-843 (2007)Vertegaal,A.C., et.al., Mol. Cell Proteomics 5 (12), 2298-2310 (2006)
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