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ACADSB Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P45954
Clone Names 90819028
Peptide ID 90819028
Additional Information
Gene ID 36
Other Names Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, SBCAD, 2-methyl branched chain acyl-CoA dehydrogenase, 2-MEBCAD, 2-methylbutyryl-coenzyme A dehydrogenase, 2-methylbutyryl-CoA dehydrogenase, ACADSB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8537b was selected from the C-term region of human ACADSB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACADSB
Function Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
Cellular Location Mitochondrion matrix.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Background

ACADSB has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. This protein can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.

References

Saenger,A.K., et.al., Biochemistry 44 (49), 16043-16053 (2005)

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$ 80.00
Cat# BP8537b
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