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CP110 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O43303
Clone Names 90904124
Peptide ID 90904124
Additional Information
Gene ID 9738
Other Names Centriolar coiled-coil protein of 110 kDa, Centrosomal protein of 110 kDa, CP110, Cep110, CCP110, CEP110, CP110, KIAA0419
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8565c was selected from the Center region of human CP110. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCP110
Synonyms CEP110, CP110, KIAA0419
Function Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation. Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Recruited early and then associates with the growing distal tips. Recruited to the mother centriole by KIF24. Removed from centrioles by TTBK2, leading to initiation of ciliogenesis
Tissue Location Highly expressed in testis. Detected at intermediate levels in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes
Research Areas
Citations (0)

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CP110 is necessary for centrosome duplication. This protein collaborates with CEP97, being involved in the suppression of a cilia assembly program. It is required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2.


Spektor,A.,, Cell 130 (4), 678-690 (2007)Chen,Z.,, Dev. Cell 3 (3), 339-350 (2002)

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$ 80.00
Cat# BP8565c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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