|Other Names||Upstream stimulatory factor 2, Class B basic helix-loop-helix protein 12, bHLHb12, FOS-interacting protein, FIP, Major late transcription factor 2, Upstream transcription factor 2, USF2, BHLHB12|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8585c was selected from the Center region of human USF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.|
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Provided below are standard protocols that you may find useful for product applications.
USF2 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. This protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs.
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)Groenen,P.M., et.al., Genomics 38 (2), 141-148 (1996)
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