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USF2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15853 |
|---|---|
| Clone Names | 90713260 |
| Gene ID | 7392 |
|---|---|
| Other Names | Upstream stimulatory factor 2, Class B basic helix-loop-helix protein 12, bHLHb12, FOS-interacting protein, FIP, Major late transcription factor 2, Upstream transcription factor 2, USF2, BHLHB12 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8585c was selected from the Center region of human USF2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | USF2 |
|---|---|
| Synonyms | BHLHB12 |
| Function | Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
USF2 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. This protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs.
References
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)Groenen,P.M., et.al., Genomics 38 (2), 141-148 (1996)
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