|Other Names||Tetraspanin-31, Tspan-31, Sarcoma-amplified sequence, TSPAN31, SAS|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8587c was selected from the Center region of human TSPAN31. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
TSPAN31 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. It is associated with tumorigenesis and osteosarcoma.
Jankowski,S.A.,et.al.,Oncogene 9 (4), 1205-1211 (1994)Ragazzini,P.,et.al.,Histol. Histopathol. 19 (2), 401-411 (2004)
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