|Other Names||4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase, HPD, PPD|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8591b was selected from the C-term region of human HPD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme in the degradation of tyrosine.|
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Provided below are standard protocols that you may find useful for product applications.
HPD is an enzyme in the catabolic pathway of tyrosine. This protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate.
Item,C.B., et.al., Mol. Genet. Metab. 91 (4), 379-383 (2007)Wistow,G., et.al., Mol. Vis. 8, 171-184 (2002)
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