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ELN Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P15502
Clone Names 90121103
Peptide ID 90121103
Additional Information
Gene ID 2006
Other Names Elastin, Tropoelastin, ELN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8594c was selected from the Center region of human ELN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELN
Function Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix. Note=Extracellular matrix of elastic fibers.
Tissue Location Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin
Research Areas
Citations (0)

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Background

ELN is one of the two components of elastic fibers. This protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues.

References

Bertram,C.et.al., Mech. Ageing Dev. 130 (10), 657-669 (2009)Wakui,H., et.al., Ren. Physiol. Biochem. 15 (1), 1-9 (1992)

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$ 80.00
Cat# BP8594c
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