PRODH Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9WU79 |
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Other Accession | O43272 |
Clone Names | 90625196 |
Gene ID | 19125 |
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Other Names | Proline dehydrogenase 1, mitochondrial, Proline oxidase, Prodh, Pro1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8620c was selected from the Center region of human PRODH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | Prodh |
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Synonyms | Pro1 |
Function | Converts proline to delta-1-pyrroline-5-carboxylate. |
Cellular Location | Mitochondrion matrix. |
Tissue Location | Expressed in liver, kidney, heart and to a lesser extent in brain, lung and muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
PRODH is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. It converts proline to delta-1-pyrroline-5-carboxylate.
References
Polyak,K., et.al., Nature 389 (6648), 300-305 (1997)Gogos,J.A., et.al., Nat. Genet. 21 (4), 434-439 (1999)
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