|Other Names||Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8621b was selected from the C-term region of human MPZ. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Found only in peripheral nervous system Schwann cells|
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Provided below are standard protocols that you may find useful for product applications.
MPZ is a major structural protein of peripheral myelin. Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.
Tachi,N., et.al., Brain Dev. 6 (6), 560-565 (1984)Hayasaka,K.,et.al., Biochem. Biophys. Res. Commun. 180 (2), 515-518 (1991)Hayasaka,K., et.al., Genomics 17 (3), 755-758 (1993)
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