|Other Names||Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein, SLP76, LCP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8655a was selected from the N-term region of human LCP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in T-cell antigen receptor mediated signaling.|
|Tissue Location||Highly expressed in spleen, thymus and peripheral blood leukocytes. Highly expressed also in T-cell and monocytic cell lines, expressed at lower level in B-cell lines Not detected in fibroblast or neuroblastoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
LCP2 is involved in T-cell antigen receptor mediated signaling.
Motto,D.G., et.al., J. Exp. Med. 183 (4), 1937-1943 (1996)Bubeck Wardenburg,J., et.al., J. Biol. Chem. 271 (33), 19641-19644 (1996)
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