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CHL1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O00533
Clone Names 90504031
Peptide ID 90504031
Additional Information
Gene ID 10752
Other Names Neural cell adhesion molecule L1-like protein, Close homolog of L1, Processed neural cell adhesion molecule L1-like protein, CHL1, CALL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8662c was selected from the Center region of human CHL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CHL1
Synonyms CALL
Function Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Soluble forms produced by cleavage/shedding also exist.
Tissue Location Expressed in the fetal and adult brain as well as in Schwann cell culture. Also detected in adult peripheral tissues.
Research Areas
Citations (0)

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CHL1 is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways.


Sakurai,K.,, Mol. Psychiatry 7 (4), 412-415 (2002)Angeloni,D.,, Am. J. Med. Genet. 86 (5), 482-485 (1999)

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$ 80.00
Cat# BP8662c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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