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DSC1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q08554
Clone Names 90504059
Peptide ID 90504059
Additional Information
Gene ID 1823
Other Names Desmocollin-1, Cadherin family member 1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC1, CDHF1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8666b was selected from the C-term region of human DSC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSC1
Synonyms CDHF1
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
Tissue Location Strongly expressed in epidermis, less in lymph node and tongue
Research Areas
Citations (0)

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DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.


Toulza,E.,, Genome Biol. 8 (6), R107 (2007)Descargues,P.,, J. Invest. Dermatol. 126 (7), 1622-1632 (2006)

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$ 80.00
Cat# BP8666b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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