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TUBA8 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NY65
Clone Names 90625253
Additional Information
Gene ID 51807
Other Names Tubulin alpha-8 chain, Alpha-tubulin 8, Tubulin alpha chain-like 2, TUBA8, TUBAL2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8675a was selected from the N-term region of human TUBA8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TUBA8
Synonyms TUBAL2
Function Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Cellular Location Cytoplasm, cytoskeleton.
Tissue Location Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain. Expressed in megakaryocytes and platelets (PubMed:34704371)
Research Areas
Citations (0)
citation

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Background

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.

References

Stanchi,F., et.al., Biochem. Biophys. Res. Commun. 270 (3), 1111-1118 (2000)Feierbach,B., et.al., J. Cell Biol. 144 (1), 113-124 (1999)

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$ 277.78
Cat# BP8675a
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