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CACNA2D1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P54289
Clone Names 90904001
Peptide ID 90904001
Additional Information
Gene ID 781
Other Names Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-gated calcium channel subunit alpha-2/delta-1, Voltage-dependent calcium channel subunit alpha-2-1, Voltage-dependent calcium channel subunit delta-1, CACNA2D1, CACNL2A, CCHL2A, MHS3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8699a was selected from the N-term region of human CACNA2D1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CACNL2A, CCHL2A, MHS3
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells Isoform 3, isoform 4 and isoform 5 are expressed in the aorta
Research Areas
Citations (0)

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CACNA2D1 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.


Williams,M.E.,, Neuron 8 (1), 71-84 (1992)Chaudhuri,D.,, J. Gen. Physiol. 129 (5), 385-401 (2007)

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$ 80.00
Cat# BP8699a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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