|Other Names||1-acyl-sn-glycerol-3-phosphate acyltransferase delta, 1-acylglycerol-3-phosphate O-acyltransferase 4, 1-AGP acyltransferase 4, 1-AGPAT 4, Lysophosphatidic acid acyltransferase delta, LPAAT-delta, AGPAT4|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8705c was selected from the Center region of human AGPAT4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus|
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Provided below are standard protocols that you may find useful for product applications.
AGPAT4 converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Leung,D.W. et.al., Front. Biosci. 6, D944-D953 (2001)Clark,H.F., et.al., Genome Res. 13 (10), 2265-2270 (2003)
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