|Other Names||PEX5-related protein, PEX2-related protein, PEX5-like protein, Peroxin-5-related protein, Peroxisome biogenesis factor 5-like, Tetratricopeptide repeat-containing Rab8b-interacting protein, Pex5Rp, TRIP8b, PEX5L, PEX5R, PXR2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8710c was selected from the Center region of human PEX5L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein Note=Some fraction is membrane associated via its interaction with RAB8B.|
|Tissue Location||Mainly expressed in brain. Also expressed in pancreas, testis and pituitary.|
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Provided below are standard protocols that you may find useful for product applications.
Wang,X., et.al., J. Biol. Chem. 279 (44), 45855-45864 (2004)
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