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BDK_1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P46663
Clone Names 90713012
Peptide ID 90713012
Additional Information
Gene ID 623
Other Names B1 bradykinin receptor, B1R, BK-1 receptor, BDKRB1, BRADYB1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8735c was selected from the Center region of human BDKRB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BDKRB1
Synonyms BRADYB1
Function This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Background

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

References

Bachvarov,D.R., et.al., Genomics 33 (3), 374-381 (1996)

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$ 80.00
Cat# BP8735c
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