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CCDC3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BQI4 |
|---|---|
| Clone Names | 90909021 |
| Gene ID | 83643 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 3, Fat/vessel-derived secretory protein, Favine, CCDC3 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8744b was selected from the C-term region of human CCDC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCDC3 |
|---|---|
| Function | Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116). Positively regulates lipid accumulation in adipose cells (By similarity). |
| Cellular Location | Secreted {ECO:0000250|UniProtKB:Q9D6Y1}. |
| Tissue Location | Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Mural,R.J., et.al., Submitted (05-JUL-2005) Celera Genomics, 45 W. Gude Dr., Rockville,MD 20850, USA
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